Understanding The Immune System

 

Phagocytes in the body

 

Granulocytes
Granulocytes, like macrophages and monocytes, are phagocytes and thus capable of enveloping and destroying invaders. Also known as polymorphonuclear leukocytes or polymorphs (because their nuclei come in "many shapes"), they contain granules filled with potent chemicals that enable them to digest microorganisms. Some of these chemicals such as histamine also contribute to acute inflammatory reactions and are responsible for the symptoms of allergy (see Allergy). Mast cells are granulocytes found in tissues, while granulocytes found in the blood include neutrophils, eosinophils, and basophils. (They are named for the way they stain in the laboratory Eosinophils, for instance, have an affinity for acidic dyes such as eosin.)

 

 

Complement

The complement system is made up of a series of about 25 proteins that work to "complement" the activity of antibodies in destroying bacteria, either by facilitating phagocytosis or by puncturing the bacterial cell membrane. Complement also helps to rid the body of antigen-antibody complexes. In carrying out these tasks, it induces an inflammatory response.